Digilab Hydroshear Plus

Digilab HydroShear Plus DNA Shearing offers the simplest, most reproducible, and most controllable method available for generating random DNA fragments. This software-driven device uses hydrodynamic shearing forces to fragment DNA strands.

With Digilab HydroShear Plus DNA Shearing, virtually any source of DNA at any concentration in volumes as small as 40μl can be randomly fractured to within a two-fold size distribution. For instance, if the desired target size is 2kb, the HydroShear Plus can be calibrated to produce a distribution centered on 2kb with 90% of the DNA falling between 1.3kb and 2.6kb – ideal for paired-end library construction. It is the best system for making long DNA fragments for single molecule sequencing.


  1. • Automated multi-port valve to allow hands-free multiple washing

  2. • Integrated holder for three wash solutions and waste

  3. • Integrated holder for sample vial